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But while these drugs have helped millions of Americans move closer to their weight loss goals, they can be accompanied by some unpleasantand often unexpectedside effects

Get emergency medical help if you have signs of an allergic reaction to Tirzepatide: More serious side effects of Tirzepatide include: (Call your doctor at once if these occur) Common Tirzepatide side effects may include: This is not a complete list of side effects and others may occur

Rotating injection sites is important to avoid complications

A clinical trial conducted in May 2025 observed patients taking either drug for 72 weeks, looking closely at their percent change in weight